A healthcare provider will administer Toposar at a hospital or other healthcare setting over a 30- to 60-minute period. It is given as a slow injection into a vein once a day or every other day for up to five days, followed by a three- to four-week break. Your dosage of Toposar will depend on your height, weight, and a number of other factors.
An Introduction to Dosing With ToposarThe dose of Toposar® (etoposide injection) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your height and weight
- The type of cancer you have
- How well you tolerate the medication
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
Toposar Dosage for Small Cell Lung CancerLike many chemotherapy medicines, Toposar dosages are based on body surface area, which is normally calculated using your height and weight. Doses based on body surface area are expressed as milligrams per meter squared (mg per m2).
The usual dose of Toposar for treating small cell lung cancer is highly individualized, and may range from 35 mg per m2 a day for 4 days to 50 mg per m2 a day for 5 days. People with kidney or liver disease are normally given lower Toposar doses.
Toposar can cause significant side effects, especially bone marrow depression (when the bone marrow is unable to produce adequate amounts of red blood cells, white blood cells, and platelets). After receiving Toposar for four to five days, you will be given a break in treatment to allow your body to recover from Toposar side effects. The "cycle" of four to five days of Toposar followed by a break will be repeated every three to four weeks, after you have recovered from potentially serious side effects. Your healthcare provider will tell you how many treatment cycles you need.