Tarceva Drug Interactions

Antacids, H2 blockers, proton pump inhibitors, and certain other drugs may cause negative interactions when combined with Tarceva. Some of these reactions can increase the risk for potentially serious side effects or decrease the effectiveness of the medicines. Your healthcare provider may need to monitor you more closely if you are undergoing Tarceva treatment, and adjust your dosage amounts as needed.

An Overview of Interactions With Tarceva

Tarceva® (erlotinib) can potentially react with a number of other medications. Some of the drugs that may interact with Tarceva include but are not limited to:
 
  • Antacids (Gaviscon®, Maalox®, Mylanta®, Tums®, and many others)
  • Corticosteroids, such as:
     
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
 
  • Medications that "thin" the blood, such as anticoagulant and antiplatelet drugs like:
     
 
 
 
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
 
 
 
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Tarceva Drug Information

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