Paclitaxel Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
paclitaxel is combined with any of the drugs listed above.
Certain Antibiotics or Antifungals
Combining certain antibiotics or antifungals with paclitaxel may increase the level of paclitaxel in your blood, potentially increasing your risk of
paclitaxel side effects. Talk to your healthcare provider before taking these medications together.
Certain Anticonvulsants
Taking certain anticonvulsants (
seizure medications) with
Taxol may decrease the level of Taxol in your blood, perhaps making it less effective. Talk to your healthcare provider before taking these medications together.
Live Vaccinations
Because chemotherapy medicines (including paclitaxel) can suppress the immune system, it is generally best to avoid live vaccinations while receiving chemotherapy.
Protease Inhibitors
Combining a protease inhibitor with paclitaxel may increase the level of paclitaxel in your blood, possibly increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.
Rifamycin Antibiotics
Taking paclitaxel with rifamycin antibiotics can affect the level of paclitaxel in your blood. Talk to your healthcare provider before taking these medications together.
Final Thoughts on Drug Interactions With Paclitaxel
It is possible that not all drug interactions with paclitaxel were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions with the medication that may apply to you.
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