Nicorette Gum Drug Interactions

Nicorette Gum Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Nicorette Gum is combined with any of the drugs listed above.
 
Benzodiazepines
If you take a benzodiazepine, you may experience more sedation and drowsiness from the benzodiazepine medication when you stop smoking. Your healthcare provider may need to decrease your benzodiazepine dose.
 
Beta Agonists
Your healthcare provider may need to adjust the dose of your beta agonist medication when you stop smoking, or when you start using Nicorette Gum. Talk to your healthcare provider about your plans for smoking cessation.
 
Beta Blockers
Beta blockers may be more effective at decreasing blood pressure and heart rate when you no longer smoke. Your healthcare provider may need to decrease the dose of your beta blocker after you quit smoking.
 
Cimetidine
Cimetidine may increase the level of nicotine in your body. If you use Nicorette Gum, talk to your healthcare provider about an alternative to cimetidine. Similar medications, such as ranitidine (Zantac®), do not interact with Nicorette Gum.
 
Clozapine
When you stop smoking, your clozapine blood levels may increase. However, because it contains nicotine, Nicorette Gum may decrease clozapine levels. Your healthcare provider may choose to monitor you more closely, or check your clozapine levels with a simple blood test, when you start using Nicorette Gum.
 
Flecainide
Flecainide blood levels may increase when you quit smoking, which could increase your risk for flecainide side effects. Talk to your healthcare provider about this possible interaction. You may need a lower flecainide dose.
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