As previously mentioned, Navelbine belongs to a group of chemotherapy medications called vinca alkaloids. Vinca alkaloids are also called antimicrotubule agents. This is because they work by preventing the formation of structures inside cells known as microtubules. Microtubules play an important role in helping cells divide and multiply.
By preventing the formation of microtubules, antimicrotubule agents, such as Navelbine, stop cells from growing and dividing and cause the cells to die.
Navelbine is not approved for use in children (usually defined as people younger than 18 years old), as it has not been adequately studied in this age group. In a small study examining the use of Navelbine for the treatment of recurrent cancerous tumors in children, the medication did not appear to be particularly effective. Side effects reported in this study were similar to the usual reported Navelbine side effects.
Navelbine can be used in older adults. About one-third of people in Navelbine clinical studies were 65 years old or older. In these studies, people 65 years old and older appeared to respond to and tolerate the medication no differently than younger age groups.
On occasion, your healthcare provider may recommend this medicine for treating something other than the conditions listed in this article. This is called an "off-label" use. Navelbine may be prescribed off-label for the treatment of other types of cancer, such as: