Lung Cancer Home > Drug Interactions With Paclitaxel

A number of medications may cause drug interactions with paclitaxel, including rifamycin antibiotics, protease inhibitors, and certain anticonvulsants. These interactions can increase the level of paclitaxel in your blood and increase your risk of developing potentially negative side effects. If drug interactions with paclitaxel are a concern, your healthcare provider may advise you to avoid certain medications or adjust your dosages.

Drug Interactions With Paclitaxel: An Overview

Paclitaxel (Taxol®) can potentially interact with other medications. Some of the medicines that may lead to paclitaxel interactions include:
  • Certain antibiotics or antifungals, including:


    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®)


  • Certain anticonvulsants, including:





  • Protease inhibitors, such as:



  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation




Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.