Nicotrol NS is a drug used to help people quit smoking. It comes in the form of a nasal spray that is administered into the nose once or twice an hour. Up to 27 percent of people who used Nicotrol NS in clinical studies were still not smoking one year later, compared to up to 15 percent of people who were given a placebo.
What Is Nicotrol NS?
Nicotrol® NS (nicotine nasal spray) is a prescription medication approved to help people quit smoking (known as smoking cessation) by reducing the uncomfortable symptoms of nicotine withdrawal that occur when people try to quit. It is sprayed into the nose. Nicotrol NS should be used as part of a complete smoking-cessation program that includes behavior change strategies, counseling, or support groups.
Nicotrol NS is a nicotine replacement medication that is sprayed into the nose. The nicotine is absorbed from the nose into the body, where it helps replace some of the nicotine your body was used to getting from cigarettes. This reduces nicotine withdrawal symptoms, such as cravings, that occur when you stop smoking.
Clinical Effects of Nicotrol NS
In clinical studies, Nicotrol NS was shown to help people quit smoking more than a placebo. In these studies, up to 58 percent of people using Nicotrol NS were able to quit smoking for at least four weeks, compared to 32 percent of people given a placebo (a medication with no active ingredients). One year later, up to 27 percent of those who had used Nicotrol NS were still not smoking, compared to up to 15 percent of people who had been given the placebo.
In addition, people given Nicotrol NS experienced more relief from nicotine withdrawal symptoms than those given the placebo. The Nicotrol NS group also had a reduced urge to smoke.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Nicotrol NS [package label]. New York, NY: Pfizer, Inc.;2010 June.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob. Accessed March 9, 2011.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed March 9, 2011.
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