Lung Cancer Home > Navelbine

If you have non-small cell lung cancer, you may benefit from treatment with Navelbine. This prescription medication is given as an injection into a vein once a week. It works by preventing the growth and multiplication of cancer cells, causing them to die. Side effects include nausea, loss of strength, and a decrease in white blood cells.

What Is Navelbine?

Navelbine® (vinorelbine) is a prescription medication approved to treat a type of lung cancer known as non-small cell lung cancer. It may be used alone or in combination with another chemotherapy medicine called cisplatin (Platinol®).
 
Navelbine contains the active ingredient vinorelbine tartrate, or simply vinorelbine. This drug belongs to a general class of chemotherapy medicines called plant alkaloids. There are several types of plant alkaloids, and Navelbine is a vinca alkaloid. Vinca alkaloids are anticancer medicines derived from the Madagascar periwinkle plant (Catharanthus roseus).
 
(Click Navelbine Uses for more information on this topic, including possible off-label uses.)
 

Who Makes This Medication?

Navelbine is made by Pierre Fabre Médicament for Pierre Fabre Pharmaceuticals, Inc.
 

How Does Navelbine Work?

Navelbine belongs to a group of chemotherapy medications called vinca alkaloids. Vinca alkaloids are also called antimicrotubule agents. This is because they work by preventing the formation of structures inside cells known as microtubules. Microtubules play an important part in helping cells divide and multiply.
 
By preventing the formation of microtubules, antimicrotubule agents, such as Navelbine, stop cells from growing and dividing, which causes the cells to die.  
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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