Navelbine belongs to the vinca alkaloid class of chemotherapy medicines, and is derived from the Madagascar periwinkle plant. It works by preventing the formation of structures inside cells known as microtubules, which are important for cells to divide and multiply. By preventing the formation of microtubules, Navelbine stops cells from growing and dividing, which causes the cells to die.
(Click Navelbine Uses for a closer look at what this drug is approved for and when it may be prescribed for unapproved uses. This article also discusses whether the medicine is safe for use in children and older adults.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Navelbine [package insert]. Parsippany, NJ: Pierre Fabre Pharmaceuticals, Inc.;2007 October.
Chabner BA, Bertino J, Cleary J, et al. Chapter 61. Cytotoxic Agents. In: Chabner BA, Brunton LL, Knollman BC, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12nd ed. New York: McGraw-Hill; 2011. http://www.accesspharmacy.com.offcampus.lib.washington.edu/content.aspx?aID=16680251. Accessed September 24, 2012.
Vinorelbine. Drug Facts and Comparisons. Drug Facts and Comparisons 4.0 [online]. 2012. Available from Wolters Kluwer Health, Inc. Accessed September 24, 2012.
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