Lung Cancer Home > Hycamtin Dosage

Several factors will affect the dose of Hycamtin you are prescribed, such as how you respond to this medication, your height and weight, the type of cancer being treated, and other medications you are taking. This chemotherapy drug comes in capsule or injection form and is typically given once daily for three to five days, every 21 days (for a certain number of cycles).

An Introduction to Dosing for Hycamtin

The dose of Hycamtin® (topotecan) that your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your height and weight
  • The type of cancer being treated
  • How you respond to Hycamtin (especially whether you develop dangerous side effects)
  • Other medications you are taking (your particular chemotherapy regimen)
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.

Recommended Hycamtin Dosage

Your healthcare provider will base your Hycamtin dose on your body surface area (which is calculated using your height and weight). The dosing amount will vary, depending on your particular chemotherapy regimen, as well as the particular type of cancer being treated. Also, your dosage may need to be reduced (or given less frequently) if you develop dangerous or intolerable Hycamtin side effects or if you have poor kidney function.
For small cell lung cancer, Hycamtin can be administered by mouth (in capsule form) or intravenously (by IV). For all other uses (see Hycamtin Uses), only the IV formulation is approved. This does not mean that your healthcare provider cannot recommend the capsule form for other uses; it simply means it is not approved for such uses (and therefore, there is no clearly established dosages for such uses).
For treating small cell lung cancer or ovarian cancer, Hycamtin is usually given once daily for five days, every 21 days. For treating cervical cancer, it is usually given once daily for three days every 21 days.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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