Precautions and Warnings With Doxorubicin

Some precautions and warnings with doxorubicin to be aware of include potential drug interactions, the safety of taking the drug while pregnant or breastfeeding, and the increased risk of developing congestive heart failure. You should not take doxorubicin if you have health conditions such as severe liver disease, severe heart failure, or a severe arrhythmia.

Doxorubicin: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking doxorubicin hydrochloride (Adriamycin®) if you have:
  • Congestive heart failure (CHF), an irregular heart rhythm (arrhythmia), or other heart problems
  • A history of low levels of white blood cells in the blood (known medically as neutropenia)
  • Any infection
  • Liver disease, including liver failure or cirrhosis
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Please note that this article refers specifically to the nonliposomal formulation of doxorubicin. For more information about warnings and precautions for the liposomal formulation (Doxil®), see Precautions and Warnings With Liposomal Doxorubicin.
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Doxorubicin Chemotherapy Drug

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