Drug Interactions With Doxorubicin
When you take certain other medicines along with doxorubicin, they may cause drug interactions. If doxorubicin is taken with medications such as "live" vaccinations, cyclosporine, and trastuzumab, it can increase your risk of side dangerous side effects (such as problems with the bone marrow and blood cells), or can lead to congestive heart failure. Therefore, be sure to talk to your healthcare provider about potential drug interactions with doxorubicin that may apply to your situation.
An Overview of Drug Interactions With DoxorubicinDoxorubicin hydrochloride (Adriamycin®, Doxil®) can potentially interact with other medications. Some of these medicines that may lead to doxorubicin interactions include:
- Cyclophosphamide (Cytoxan®, Neosar®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Cytarabine (Cytosar-U®)
- "Live" vaccinations, including:
o FluMist® (the nasal vaccine for influenza; the injected vaccine is not "live")o Smallpox vaccineo BCG vaccine (used in some countries for tuberculosis)
- Paclitaxel (Onxol®, Taxol®)
- Phenobarbital (Luminal®)
- Phenytoin (Dilantin®, Phenytek®)
- Streptozosin (Zanosar®)
- Trastuzumab (Herceptin®)
- Verapamil (Calan®, Calan SR®, Covera-HS®, Isoptin SR®, Verelan®, Verelan PM®).